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A Randomised, Open-label Four-way Crossover Study to Evaluate Relative Bioavailability of Tiotropium and Salmeterol After Inhalation of a Fixed Combined Single Dose (7.5 μg Tiotropium, 25 μg Salmeterol, Inhalation Powder, Hard Capsule, HandiHaler2), a Free Combined Single Dose of 18 μg Tiotropium [Spiriva HandiHaler] and 50 μg Salmeterol [Serevent Diskus], a Single Dose of 50μg Salmeterol (Serevent Diskus) and a Single Dose of 18 μg Tiotropium (Spiriva HandiHaler) in Healthy Male Volunteers

Trial Profile

A Randomised, Open-label Four-way Crossover Study to Evaluate Relative Bioavailability of Tiotropium and Salmeterol After Inhalation of a Fixed Combined Single Dose (7.5 μg Tiotropium, 25 μg Salmeterol, Inhalation Powder, Hard Capsule, HandiHaler2), a Free Combined Single Dose of 18 μg Tiotropium [Spiriva HandiHaler] and 50 μg Salmeterol [Serevent Diskus], a Single Dose of 50μg Salmeterol (Serevent Diskus) and a Single Dose of 18 μg Tiotropium (Spiriva HandiHaler) in Healthy Male Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 09 Oct 2014

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At a glance

  • Drugs Salmeterol/tiotropium bromide (Primary) ; Salmeterol; Tiotropium bromide
  • Indications Chronic obstructive pulmonary disease
  • Focus Pharmacokinetics
  • Sponsors Boehringer Ingelheim
  • Most Recent Events

    • 09 Oct 2014 New trial record
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