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An Open-label, Multicenter, Dose-escalation, Phase 1b/2 Study of the Safety, Efficacy, Pharmacodynamics, and Pharmacokinetics of RTA 408 in Combination With Ipilimumab or Nivolumab in the Treatment of Patients With Unresectable or Metastatic Melanoma

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Trial Profile

An Open-label, Multicenter, Dose-escalation, Phase 1b/2 Study of the Safety, Efficacy, Pharmacodynamics, and Pharmacokinetics of RTA 408 in Combination With Ipilimumab or Nivolumab in the Treatment of Patients With Unresectable or Metastatic Melanoma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 07 Feb 2024

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At a glance

  • Drugs Ipilimumab (Primary) ; Nivolumab (Primary) ; Omaveloxolone (Primary)
  • Indications Malignant melanoma
  • Focus Therapeutic Use
  • Acronyms REVEAL
  • Sponsors Reata Pharmaceuticals

    • Most Recent Events

    • 04 Sep 2018 Status changed from active, no longer recruiting to completed.
    • 11 Jun 2018 Status changed from recruiting to active, no longer recruiting.
    • 11 Dec 2017 Interim result from phase 1b portion of the this trial presented in a Reata Pharmaceuticals Media Release.

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