An Exploratory Pilot Study of Nab-paclitaxel Based Induction Chemotherapy Followed by Response-Stratified Locoregional Therapy for Patients With Stage III and IV HPV-Related Oropharyngeal Cancer - the OPTIMA HPV Trial

Trial Profile

An Exploratory Pilot Study of Nab-paclitaxel Based Induction Chemotherapy Followed by Response-Stratified Locoregional Therapy for Patients With Stage III and IV HPV-Related Oropharyngeal Cancer - the OPTIMA HPV Trial

Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 13 Mar 2018

At a glance

  • Drugs Paclitaxel (Primary) ; Carboplatin; Cisplatin; Fluorouracil; Hydroxycarbamide
  • Indications Head and neck cancer; Human papillomavirus infections; Oropharyngeal cancer
  • Focus Therapeutic Use
  • Acronyms OPTIMA
  • Most Recent Events

    • 07 Mar 2018 Planned End Date changed from 1 Jun 2018 to 1 Dec 2021.
    • 07 Mar 2018 Planned primary completion date changed from 1 May 2018 to 1 Dec 2018.
    • 13 Feb 2018 Results published in the American Society for Radiation Oncology media release.
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