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JAK Inhibitor Prior to Allogeneic Stem Cell Transplant for Patients With Primary and Secondary Myelofibrosis: A Prospective Study

Trial Profile

JAK Inhibitor Prior to Allogeneic Stem Cell Transplant for Patients With Primary and Secondary Myelofibrosis: A Prospective Study

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 08 Apr 2019

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At a glance

  • Drugs Ruxolitinib (Primary) ; Busulfan; Cyclophosphamide; Fludarabine; Melphalan; Methotrexate; Mycophenolate mofetil; Mycophenolate mofetil; Tacrolimus; Tacrolimus
  • Indications Myelofibrosis
  • Focus Therapeutic Use
  • Most Recent Events

    • 08 Apr 2019 Results (n=28) assessing pre-hematopoietic cell transplant Ruxolitinib in patients with mylelofibrosis published in the Bone Marrow Transplantation
    • 27 Mar 2019 Planned primary completion date changed from 1 Mar 2019 to 11 Mar 2021.
    • 15 Jan 2019 Planned number of patients changed from 33 to 48.
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