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A Randomized, Blinded, Placebo-controlled, Two-Phase, Sequential Cohort, Dose Finding Study to Assess the Safety and Efficacy of an Oral Thrombopoietin Receptor Agonist, Eltrombopag (SB-497115-GR), Administered to Patients With Solid Tumors Receiving Gemcitabine Monotherapy or the Combination of Gemcitabine Plus Carboplatin or Cisplatin
A Randomized, Blinded, Placebo-controlled, Two-Phase, Sequential Cohort, Dose Finding Study to Assess the Safety and Efficacy of an Oral Thrombopoietin Receptor Agonist, Eltrombopag (SB-497115-GR), Administered to Patients With Solid Tumors Receiving Gemcitabine Monotherapy or the Combination of Gemcitabine Plus Carboplatin or Cisplatin
Status:Completed
Phase of Trial:
Phase II
Latest Information Update:11 Feb 2019
Price :
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At a glance
Drugs
Eltrombopag (Primary)
Indications
Solid tumours; Thrombocytopenia
Focus
Adverse reactions; Therapeutic Use
Sponsors
GlaxoSmithKline
Most Recent Events
01 Dec 2017
Primary endpoint (Phase II: Effect of eltrombopag compared to placebo on the scheduled Day 1 pre-chemotherapy platelet counts will be evaluated across all cycles in the study) has not been met, according to the results published in the International Journal of Hematology
01 Dec 2017
Results published in the International Journal of Hematology
20 Apr 2016
Time frame for primary endpoints has been changed.
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