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A Phase 3 Confirmatory Study Investigating the Efficacy and Safety of Dupilumab Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

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Trial Profile

A Phase 3 Confirmatory Study Investigating the Efficacy and Safety of Dupilumab Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 27 Mar 2024

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At a glance

  • Drugs Dupilumab (Primary)
  • Indications Atopic dermatitis
  • Focus Registrational; Therapeutic Use
  • Acronyms Liberty AD Solo 1; SOLO 1
  • Sponsors Regeneron Pharmaceuticals

    • Most Recent Events

    • 26 Feb 2024 Results of pooled analysis of LIBERTY AD PRESCHOOL,LIBERTY AD PEDS , LIBERTYAD ADOL , LIBERTY AD SOLO1,LIBERTYADSOLO2 reporting serum CCL17/TARC (human TARC Quantikine ELISA kit; R&D Systems) levels from patients with moderate-to-severe or severe AD, presented at the 2024 Annual Meeting of the American Academy of Allergy, Asthma and Immunology
    • 27 Feb 2023 Results of pooled analysis (from 6 phase 3 studies (NCT03346434, NCT03345914, NCT03054428, NCT02260986, NCT02277743 and NCT02277769) assessing IgE levels in patients aged 6 months and older with moderate-to-severe AD presented at the 2023 Annual Meeting of the American Academy of Allergy, Asthma and Immunology.
    • 20 Feb 2023 Post-hoc pooled data (N=2444) analysis evaluating efficacy and safety of dupilumab in patients aged greater than or equal to 60 years with moderate-to-severe atopic dermatitis from NCT02277743, NCT02277769, NCT02755649, NCT02260986, published in the American Journal of Clinical Dermatology.

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