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A Phase-I, Dose Escalation Study of Recombinant Human Interleukin-18 (Sb-485232) Combined With Adoptive Transfer of Vaccine-Primed CD3/CD28-Costimulated Autologous T-Cells Following Lymphodepletion for Adult Patients With Recurrent Ovarian, Fallopian Tube or Primary Peritoneal Cancer

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Trial Profile

A Phase-I, Dose Escalation Study of Recombinant Human Interleukin-18 (Sb-485232) Combined With Adoptive Transfer of Vaccine-Primed CD3/CD28-Costimulated Autologous T-Cells Following Lymphodepletion for Adult Patients With Recurrent Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Status: Withdrawn prior to enrolment
Phase of Trial: Phase I

Latest Information Update: 31 Mar 2023

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At a glance

  • Drugs CD3 CD28 autologous T cells (Primary) ; Iboctadekin (Primary)
  • Indications Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Adverse reactions
  • Most Recent Events

    • 06 Dec 2016 Planned primary completion date changed from 1 Sep 2021 to 1 Jun 2015.
    • 06 Dec 2016 Status changed from completed to withdrawn prior to enrolment.
    • 01 Jul 2015 Status changed from recruiting to completed as reported by ClinicalTrials.gov record.

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