Trial Profile

A Phase 1 Study of Milademetan (DS 3032b), an Oral MDM2 Inhibitor, In Dose Escalation as a Single Agent and In Dose Escalation/Expansion In Combination With 5 Azacitidine In Subjects With Acute Myelogenous Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

Status: Discontinued

Phase of Trial: Phase I

Latest Information Update: 20 Feb 2024

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At a glance

14 May 2021 Status changed from active, no longer recruiting to discontinued.
08 Dec 2020 Results assessing clonal expansion of mutant p53 clones by MDM2 inhibition in acute myeloid leukemias, presented at the 62nd Annual Meeting and Exposition of the American Society of Hematology
08 May 2020 Status changed from recruiting to active, no longer recruiting.

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