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Induction FOLFOX with or without Aflibercept followed by chemoradiation in High Risk Locally Advanced Rectal Cancer. Phase II randomized, multicenter, open label trial

Trial Profile

Induction FOLFOX with or without Aflibercept followed by chemoradiation in High Risk Locally Advanced Rectal Cancer. Phase II randomized, multicenter, open label trial

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Aflibercept (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Rectal cancer
  • Focus Therapeutic Use
  • Acronyms RIA study

Most Recent Events

  • 16 Mar 2021 Results published in the Clinical Cancer Research
  • 31 May 2020 Results of 3-year disease-free suvival and retrospective analysis by molecular subtypes presented at the 56th Annual Meeting of the American Society of Clinical Oncology.
  • 04 Feb 2020 Status changed from active, no longer recruiting to completed.

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