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A Pilot Study of Talazoparib as a Neoadjuvant Study in Patients With a Diagnosis of Invasive Breast Cancer and a Deleterious BRCA Mutation

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Trial Profile

A Pilot Study of Talazoparib as a Neoadjuvant Study in Patients With a Diagnosis of Invasive Breast Cancer and a Deleterious BRCA Mutation

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 08 Jul 2022

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At a glance

  • Drugs Talazoparib (Primary)
  • Indications Adenocarcinoma; Early breast cancer
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 23 Jun 2022 Results (n=13) assessing the changes in the tumor immune microenvironment (TiME) induced by talazoparib, published in the Clinical Cancer Research.
  • 16 Jun 2022 Status changed from active, no longer recruiting to completed.
  • 09 Feb 2022 Planned End Date changed from 30 Apr 2021 to 30 Apr 2022.

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