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A phase I study of PXL 770 in healthy volunteers

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Trial Profile

A phase I study of PXL 770 in healthy volunteers

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 31 Jan 2017

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At a glance

  • Drugs PXL 770 (Primary)
  • Indications Type 2 diabetes mellitus
  • Focus Adverse reactions; Proof of concept
  • Sponsors Poxel

Most Recent Events

  • 27 Jan 2017 According to a Poxel media release, the company anticipates to continue the study during the second half of this year.
  • 15 Sep 2016 According to a Poxel media release, during the study the company observed a different metabolic pattern in humans compared to animals that were treated with PXL770. Therefore, based on regulatory guidelines, Poxel will need to further evaluate the profile of the metabolites, prior to starting the second part of the phase I study. As a result of this additional preclinical work, the start of the second part of the Phase Ib study will be delayed until 2017.
  • 20 Jun 2016 Results from the first stage of the study (n=64) published in a Poxel media release.

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