Trial Profile

Phase II Study of the PARP Inhibitor Talazoparib in Advanced Cancer Patients With Somatic Alterations in BRCA1/2, Mutations/Deletions in Other BRCA Pathway Genes and Germline Mutation in BRCA1/2 (Not Breast or Ovarian Cancer)

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 20 Jan 2026

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At a glance

Drugs Talazoparib (Primary)
Indications Bladder cancer; Carcinoma; Cholangiocarcinoma; Sarcoma; Solid tumours
Focus Therapeutic Use

02 Jan 2026 Planned End Date changed from 31 Dec 2025 to 31 Dec 2026.
02 Jan 2026 Planned primary completion date changed from 31 Dec 2025 to 31 Dec 2026.
14 Jun 2023 Planned End Date changed from 31 Dec 2023 to 31 Dec 2025.

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