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An Open-label Phase 2 Study to Assess the Effect of C5aR Antagonist Therapy by CCX168 Oral Administration on ex Vivo Thrombus Formation and Disease Activity in ESRD Patients With Atypical Hemolytic Uremic Syndrome

Trial Profile

An Open-label Phase 2 Study to Assess the Effect of C5aR Antagonist Therapy by CCX168 Oral Administration on ex Vivo Thrombus Formation and Disease Activity in ESRD Patients With Atypical Hemolytic Uremic Syndrome

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Avacopan (Primary)
  • Indications Atypical Haemolytic Uraemic Syndrome
  • Focus Proof of concept; Therapeutic Use
  • Acronyms ACCESS
  • Sponsors ChemoCentryx

Most Recent Events

  • 02 Mar 2017 Status changed from recruiting to discontinued.
  • 07 Nov 2016 According to ChemoCentryx media release, the company has announced positive data (n=5) from this pilot phase II trial.
  • 08 Aug 2016 According to a ChemoCentryx media release, the company expects to report early results from this trial in late 2016.

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