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A Phase II Randomized Study Evaluating the Biological and Clinical Effects of the Combination of Palbociclib With Letrozole as Neoadjuvant Therapy in Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer

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Trial Profile

A Phase II Randomized Study Evaluating the Biological and Clinical Effects of the Combination of Palbociclib With Letrozole as Neoadjuvant Therapy in Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 Jan 2023

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At a glance

  • Drugs Letrozole (Primary) ; Palbociclib (Primary)
  • Indications Early breast cancer
  • Focus Pharmacodynamics; Therapeutic Use
  • Acronyms PALLET

    • Most Recent Events

    • 13 Oct 2021 Results published in the Clinical Cancer Research
    • 15 Apr 2021 Status changed from active, no longer recruiting to completed.
    • 11 Dec 2020 Results assessing identification of biomarker of de novo resistance to palbociclib presented at the 43rd Annual San Antonio Breast Cancer Symposium

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