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A Phase 1, Open-Label Fixed-Sequence 2-Period Crossover Study Of Palbociclib (pd-0332991) In Healthy Volunteers To Estimate The Effect Of Antacid Treatment On The Bioavailability Of A 125 Mg Single Dose Of Six Experimental Formulations Of Palbociclib Relative To Palbociclib Administration Alone Under Fasted Conditions

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A Phase 1, Open-Label Fixed-Sequence 2-Period Crossover Study Of Palbociclib (pd-0332991) In Healthy Volunteers To Estimate The Effect Of Antacid Treatment On The Bioavailability Of A 125 Mg Single Dose Of Six Experimental Formulations Of Palbociclib Relative To Palbociclib Administration Alone Under Fasted Conditions

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Palbociclib (Primary) ; Rabeprazole
  • Indications Acute myeloid leukaemia; Bone metastases; Brain metastases; Breast cancer; Cancer; Colorectal cancer; Gastrointestinal stromal tumours; Malignant melanoma; Mantle-cell lymphoma; Non-small cell lung cancer; Pancreatic cancer; Precursor cell lymphoblastic leukaemia-lymphoma; Prostate cancer; Solid tumours; Squamous cell cancer; Urogenital cancer
  • Focus Pharmacokinetics
  • Sponsors Pfizer

    • Most Recent Events

    • 14 May 2015 Status changed from recruiting to completed as reported by ClinicalTrials.gov record.
    • 17 Feb 2015 Status changed from not yet recruiting to recruiting, according to ClinicalTrials.gov record.
    • 13 Dec 2014 New trial record

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