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A Multicenter, Randomized Phase ll Study of Letrozole Versus Letrozole Plus Everolimus for Hormone Receptor-PositivePremenopausal Women With Recurrent or Metastatic Breast Cancer on Goserelin Treatment After Progression on Tamoxifen

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Trial Profile

A Multicenter, Randomized Phase ll Study of Letrozole Versus Letrozole Plus Everolimus for Hormone Receptor-PositivePremenopausal Women With Recurrent or Metastatic Breast Cancer on Goserelin Treatment After Progression on Tamoxifen

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 27 Sep 2023

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At a glance

  • Drugs Everolimus (Primary) ; Letrozole
  • Indications Advanced breast cancer
  • Focus Therapeutic Use
  • Acronyms MIRACLE

    • Most Recent Events

    • 14 Dec 2019 Primary endpoint has been met. (Progression free survival)
    • 14 Dec 2019 Status changed from not yet recruiting to completed, according to results presented at the 42nd Annual San Antonio Breast Cancer Symposium
    • 14 Dec 2019 Results assessing use of everolimus plus letrozole in advanced premenopausal breast cancer patients presented at the 42nd Annual San Antonio Breast Cancer Symposium
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