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An Exploratory/Proof of Concept Investigation of the Safety and Pharmacodynamics of LY2127399 in HLA-Presensitized Patients With End-Stage Renal Disease Awaiting Transplantation

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An Exploratory/Proof of Concept Investigation of the Safety and Pharmacodynamics of LY2127399 in HLA-Presensitized Patients With End-Stage Renal Disease Awaiting Transplantation

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Tabalumab (Primary)
  • Indications Renal failure; Renal transplant rejection
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 18 Jan 2016 Primary endpoint of change from baseline through 76 weeks in Panel Reactive Antibodies (PRA) has been met, according to resultd published in the American Journal of Transplantation.
    • 18 Jan 2016 Results published in the American Journal of Transplantation
    • 19 Dec 2014 New trial record

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