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A Placebo-Controlled, Double-Blind, Parallel-Group, Randomized, Proof-of-Concept, Dose-Finding Study To Evaluate Safety, Tolerability, and Efficacy of E2609 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease (Prodromal Alzheimer's Disease) and Mild to Moderate Dementia Due to Alzheimer's Disease

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Trial Profile

A Placebo-Controlled, Double-Blind, Parallel-Group, Randomized, Proof-of-Concept, Dose-Finding Study To Evaluate Safety, Tolerability, and Efficacy of E2609 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease (Prodromal Alzheimer's Disease) and Mild to Moderate Dementia Due to Alzheimer's Disease

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Elenbecestat (Primary)
  • Indications Alzheimer's disease; Dementia; Mild cognitive impairment
  • Focus Adverse reactions
  • Sponsors Eisai Inc

Most Recent Events

  • 02 Dec 2019 According to an Eisai Inc media release, results from this trial will be presented at 12th Clinical Trials on Alzheimers Disease (CTAD) conference taking place in San Diego, California in the United States, from December 4 to 7, 2019.
  • 13 Sep 2019 Status changed from active, no longer recruiting to discontinued, according to an Eisai Co Ltd media release.
  • 13 Sep 2019 According to an Eisai Co Ltd media release, this trial has been discontinued by Eisai and Biogen as a consequence of the discontinuation of MISSION AD1 and MISSION AD2 trials. The MISSION trials have been discontinued as per the recommendation of the Data Safety Monitoring Board (DSMB) due to unfavorable risk-benefit ratio.

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