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A Single-Center, Randomized, Double-Blind, Single and Multiple Ascending Dose, Placebo-Controlled Study to Investigate the Safety, Tolerability and Pharmacokinetics of RO6889678 and the Combination of RO6889678 With Ritonavir Following Oral Administration, the Effect of Food on the Pharmacokinetics of RO6889678 and the Effect of Multiple Oral Dosing of RO6889678 and the Combination of RO6889678 With Ritonavir on the Pharmacokinetics of Midazolam in Healthy Subjects

Trial Profile

A Single-Center, Randomized, Double-Blind, Single and Multiple Ascending Dose, Placebo-Controlled Study to Investigate the Safety, Tolerability and Pharmacokinetics of RO6889678 and the Combination of RO6889678 With Ritonavir Following Oral Administration, the Effect of Food on the Pharmacokinetics of RO6889678 and the Effect of Multiple Oral Dosing of RO6889678 and the Combination of RO6889678 With Ritonavir on the Pharmacokinetics of Midazolam in Healthy Subjects

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 07 Apr 2017

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At a glance

  • Drugs Ritonavir (Primary) ; RO 6889678 (Primary) ; Midazolam
  • Indications Unspecified
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Roche

Most Recent Events

  • 03 Apr 2017 Status changed from completed to discontinued.
  • 01 Dec 2015 Status changed from recruiting to completed as pe ClinicalTrials.gov record.
  • 31 Jul 2015 Planned End Date changed from 1 Oct 2015 to 1 Jan 2016 as reported by ClinicalTrials.gov

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