An Open-Label, Multicenter, Dose-Escalation Phase I Study to Evaluate the Safety, Pharmacokinetics, and Therapeutic Activity of RO6958688, A Novel T-cell Bispecific Antibody That Targets the Human Carcinoembryonic Antigen (CEA) on Tumor Cells and CD3 on T Cells, Administered Intravenously in Patients With Locally Advanced and/or Metastatic CEA(+) Solid Tumors

Trial Profile

An Open-Label, Multicenter, Dose-Escalation Phase I Study to Evaluate the Safety, Pharmacokinetics, and Therapeutic Activity of RO6958688, A Novel T-cell Bispecific Antibody That Targets the Human Carcinoembryonic Antigen (CEA) on Tumor Cells and CD3 on T Cells, Administered Intravenously in Patients With Locally Advanced and/or Metastatic CEA(+) Solid Tumors

Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 23 Jun 2018

At a glance

  • Drugs RO 6958688 (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Sponsors Roche
  • Most Recent Events

    • 01 May 2018 Planned End Date changed from 27 Apr 2018 to 31 Aug 2019.
    • 01 May 2018 Planned primary completion date changed from 27 Apr 2018 to 31 Aug 2019.
    • 01 May 2018 Status changed from recruiting to active, no longer recruiting.
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