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Safety, Tolerability, Preliminary Pharmacokinetics and Pharmacodynamics of Single Ascending Oral Doses of MYK-461 in Patient Volunteers With Hypertrophic Cardiomyopathy

Trial Profile

Safety, Tolerability, Preliminary Pharmacokinetics and Pharmacodynamics of Single Ascending Oral Doses of MYK-461 in Patient Volunteers With Hypertrophic Cardiomyopathy

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 23 Dec 2016

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At a glance

  • Drugs Mavacamten (Primary)
  • Indications Dilated cardiomyopathy; Hypertrophic cardiomyopathy
  • Focus Adverse reactions
  • Sponsors MyoKardia
  • Most Recent Events

    • 16 Nov 2016 Results from NCT02329184 and NCT02356289 studies, presented at the 89th Annual Scientific Sessions of the American Heart Association.
    • 11 Jul 2016 Results from this trial have been submitted for presentation at The American Heart Association's Scientific Sessions 2016, according to a MyoKardia media release.
    • 11 Jul 2016 Results published in a MyoKardia media release.
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