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An Open-label Study in Healthy Male Subjects to Assess the Effect of Hyperthyroidism Mimicked by Oral Dosing of Levothyroxine on the Pharmacokinetics of Sorafenib

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An Open-label Study in Healthy Male Subjects to Assess the Effect of Hyperthyroidism Mimicked by Oral Dosing of Levothyroxine on the Pharmacokinetics of Sorafenib

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Oct 2021

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At a glance

  • Drugs Sorafenib (Primary) ; Levothyroxine sodium
  • Indications Acute myeloid leukaemia; Acute promyelocytic leukaemia; Breast cancer; Chronic lymphocytic leukaemia; Colorectal cancer; Gastric cancer; Germ cell and embryonal neoplasms; Germ cell cancer; Glioma; Head and neck cancer; Liver cancer; Myelodysplastic syndromes; Neuroendocrine tumours; Neurofibromatoses; Non-small cell lung cancer; Ovarian cancer; Renal cancer; Soft tissue sarcoma; Thyroid cancer
  • Focus Pharmacokinetics
  • Sponsors Bayer

    • Most Recent Events

    • 09 Oct 2015 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 15 Jul 2015 Planned End Date changed from 1 May 2015 to 1 Sep 2015 as reported by ClinicalTrials.gov.
    • 27 Apr 2015 Planned primary completion date changed from 1 Apr 2015 to 1 May 2015.as reported by ClinicalTrials.gov record.

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