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A PHASE I, OPEN-LABEL, NON-RANDOMIZED, DOSE-ESCALATING, SAFETY, TOLERABILITY, PHARMACOKINETIC, PHARMACODYNAMIC AND EFFICACY STUDY OF TAS-120 IN PATIENTS WITH ADVANCED SOLID TUMORS

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Trial Profile

A PHASE I, OPEN-LABEL, NON-RANDOMIZED, DOSE-ESCALATING, SAFETY, TOLERABILITY, PHARMACOKINETIC, PHARMACODYNAMIC AND EFFICACY STUDY OF TAS-120 IN PATIENTS WITH ADVANCED SOLID TUMORS

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 20 Feb 2023

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At a glance

  • Drugs Futibatinib (Primary)
  • Indications Biliary cancer; Bladder cancer; Cholangiocarcinoma; Colorectal cancer; Gastric cancer; Lung cancer; Oesophageal cancer; Pancreatic cancer; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Taiho Pharmaceutical

    • Most Recent Events

    • 01 Feb 2023 Results (n=83) assessing safety and efficacy of futibatinib in Japanese patients with advanced solid tumors, published in the Cancer Science.
    • 21 Sep 2021 Results (n=44; as of 26 Nov 2020) presented at the 46th European Society for Medical Oncology Congress.
    • 13 Sep 2021 According to a Taiho Oncology media release, result of pooled analysis from this study assessing safety profile of futibatinib and initial results from this study will be presented at the European Society for Medical Oncology (ESMO) Congress 2021. Results will be shared as a poster presentation on September 16, 2021. The abstract for this presentation is available on the ESMO website

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