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An Open Label Positron Emission Tomography (PET) Imaging Study Using 89Zirconium to Investigate the Biodistribution of Anti-HER3 Monoclonal Antibody (mAb) GSK2849330 and Characterize Its Dose-receptor Occupancy Relationship in Subjects With Advanced HER3-Positive Solid Tumors

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Trial Profile

An Open Label Positron Emission Tomography (PET) Imaging Study Using 89Zirconium to Investigate the Biodistribution of Anti-HER3 Monoclonal Antibody (mAb) GSK2849330 and Characterize Its Dose-receptor Occupancy Relationship in Subjects With Advanced HER3-Positive Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 29 Aug 2023

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At a glance

  • Drugs GSK 2849330 (Primary)
  • Indications Advanced breast cancer; Cervical cancer; Colorectal cancer; Head and neck cancer; Ovarian cancer; Prostate cancer; Solid tumours
  • Focus Diagnostic use
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 16 Aug 2016 Status changed from recruiting to completed.
    • 21 Apr 2016 Planned End Date changed from 1 Sep 2017 to 1 Sep 2016.
    • 21 Apr 2016 Planned primary completion date changed from 1 Sep 2017 to 1 Sep 2016.
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