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An Open-label, Single-arm, Pilot Study to Evaluate the Effect of XmAb5871 on Disease Activity in Patients With IgG4-Related Disease.

Trial Profile

An Open-label, Single-arm, Pilot Study to Evaluate the Effect of XmAb5871 on Disease Activity in Patients With IgG4-Related Disease.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 02 Jan 2024

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At a glance

  • Drugs Obexelimab (Primary)
  • Indications Immunoglobulin G4-related disease
  • Focus Therapeutic Use
  • Sponsors Xencor

Most Recent Events

  • 15 Nov 2023 Results of a PopPK model analysis from four clinical trials: a first-in-human, single-ascending dose study in healthy volunteers; 2) a multiple-ascending dose study in patients with RA; 3) an open-label study in patients with IgG4-RD; and 4) a PK and relative bioavailability study.
  • 01 Aug 2023 Results presented in the Zenas Biopharma Media Release.
  • 01 Aug 2023 According to a Zenas Biopharma media release, results from this trial were published in the Lancet Rheumatology.

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