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A Randomized Multicenter Phase II Trial to Evaluate the Safety and Immunogenicity of Two Doses of Vaccination With Folate Receptor Alpha Peptides With GM-CSF in Patients With Triple Negative Breast Cancer Defined as Primary Tumor That is Her2-neu and Low (< 10%) ER/PR Nuclear Staining

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A Randomized Multicenter Phase II Trial to Evaluate the Safety and Immunogenicity of Two Doses of Vaccination With Folate Receptor Alpha Peptides With GM-CSF in Patients With Triple Negative Breast Cancer Defined as Primary Tumor That is Her2-neu and Low (< 10%) ER/PR Nuclear Staining

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Granulocyte-macrophage colony-stimulating factors (Primary) ; TPIV 200 (Primary) ; Cyclophosphamide
  • Indications Advanced breast cancer; Early breast cancer; Triple negative breast cancer
  • Focus Pharmacodynamics; Proof of concept
  • Sponsors Marker Therapeutics Inc

    • Most Recent Events

    • 15 Jul 2021 Status changed from active, no longer recruiting to completed.
    • 21 Apr 2021 Planned End Date changed from 1 Dec 2021 to 1 Aug 2021.
    • 21 Apr 2021 Planned primary completion date changed from 1 Dec 2021 to 1 Aug 2021.

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