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An Open-label,Phase I, Dose-escalation Trial to Evaluate the Safety, Tolerability, Maximum Tolerated Dose, Pharmacokinetic, and Pharmacodynamics of the Anti-FGFR2 Antibody Drug Conjugate BAY1187982 in Subjects With Advanced Solid Tumors Known to Express FGFR2.

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An Open-label,Phase I, Dose-escalation Trial to Evaluate the Safety, Tolerability, Maximum Tolerated Dose, Pharmacokinetic, and Pharmacodynamics of the Anti-FGFR2 Antibody Drug Conjugate BAY1187982 in Subjects With Advanced Solid Tumors Known to Express FGFR2.

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Aprutumab ixadotin (Primary)
  • Indications Advanced breast cancer; Male breast cancer; Solid tumours; Triple negative breast cancer
  • Focus Adverse reactions; First in man
  • Sponsors Bayer

    • Most Recent Events

    • 09 Sep 2019 Results assessing safety, tolerability and maximum tolerated dose of aprutumab ixadotin published in the Targeted Oncology
    • 05 Apr 2017 Results presented at the 108th Annual Meeting of the American Association for Cancer Research
    • 30 Aug 2016 Status changed from active, no longer recruiting to discontinued.

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