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A phase I followed by a randomized phase II trial of two cycles carboplatin-olaparib followed by olaparib monotherapy versus capecitabine in BRCA-1 or -2 mutated Her2 negative advanced breast cancer as first line treatment (REVIVAL study)

Trial Profile

A phase I followed by a randomized phase II trial of two cycles carboplatin-olaparib followed by olaparib monotherapy versus capecitabine in BRCA-1 or -2 mutated Her2 negative advanced breast cancer as first line treatment (REVIVAL study)

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 21 Sep 2021

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At a glance

  • Drugs Olaparib (Primary) ; Capecitabine; Carboplatin; Eribulin; Paclitaxel; Vinorelbine
  • Indications Advanced breast cancer; Colorectal cancer; Malignant melanoma; Oesophageal cancer; Ovarian cancer
  • Focus Adverse reactions
  • Acronyms REVIVAL study

Most Recent Events

  • 06 Jun 2021 This trial has been discontinued in Netherlands, as per European Clinical Trials Database record.
  • 04 Jun 2019 Results presented at the 55th Annual Meeting of the American Society of Clinical Oncology
  • 14 Jan 2019 Status changed from recruiting to completed.

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