Trial Profile

Phase I Study of Escalating Doses of XL888 With Vemurafenib Plus Cobimetinib for Patients With Unresectable BRAF Mutated Stage III/IV Melanoma

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 10 Mar 2026

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At a glance

Drugs Cobimetinib (Primary) ; Vemurafenib (Primary) ; XL 888 (Primary)
Indications Malignant melanoma
Focus Adverse reactions

Most Recent Events

02 Mar 2026 Planned End Date changed from 1 Nov 2026 to 4 Nov 2026.
08 Dec 2025 Planned End Date changed from 1 Nov 2025 to 1 Nov 2026.
22 Apr 2025 Planned End Date changed from 1 Mar 2025 to 1 Nov 2025.

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