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A Phase II, Open-label, Single Arm, Multicentre, International Trial of Sofosbuvir (SOF) and GS-5816 for People With Chronic Hepatitis C Virus Infection and Recent Injection Drug Use

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Trial Profile

A Phase II, Open-label, Single Arm, Multicentre, International Trial of Sofosbuvir (SOF) and GS-5816 for People With Chronic Hepatitis C Virus Infection and Recent Injection Drug Use

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 20 Aug 2024

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At a glance

  • Drugs Sofosbuvir/velpatasvir (Primary)
  • Indications Hepatitis C
  • Focus Therapeutic Use
  • Acronyms SIMPLIFY

    • Most Recent Events

    • 12 Mar 2020 Results (n=177) assessing incidence of HCV reinfection and associated factors in two studies (SIMPLIFY and D3FEAT), published in the Clinical Infectious Diseases.
    • 02 Nov 2019 Results evaluating adherence to DAA therapy and associated factors published in the Clinical Infectious Diseases
    • 11 Jul 2019 Results of pooled analysis of two trials (SIMPLIFY and D3FEAT) evaluating the efficacy and safety of HCV DAA treatment and its impact on clinical and non-clinical outcomes in HCV-infected people with recent injecting drug use or currently receiving opioid agaonist treatment published in the Clinical Infectious Diseases

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