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A Phase 2a, Randomized, Double-blinded, Placebo-Controlled Study to Evaluate the Antiviral Activity, Safety, and Pharmacokinetics of Repeated Doses of Orally Administered JNJ 53718678 Against Respiratory Syncytial Virus Infection in the Virus Challenge Model in Healthy Adult Subjects

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A Phase 2a, Randomized, Double-blinded, Placebo-Controlled Study to Evaluate the Antiviral Activity, Safety, and Pharmacokinetics of Repeated Doses of Orally Administered JNJ 53718678 Against Respiratory Syncytial Virus Infection in the Virus Challenge Model in Healthy Adult Subjects

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Nov 2019

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At a glance

  • Drugs Rilematovir (Primary)
  • Indications Respiratory syncytial virus infections
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Janssen Sciences Ireland UC

    • Most Recent Events

    • 19 Apr 2018 Primary endpoint (Area Under the Viral Load-time Curve (VL AUC)(JNJ-53718678, 200mg vs placebo)) has been met as per the results published in the Journal of Infectious Diseases.
    • 19 Apr 2018 Results published in the Journal of Infectious Diseases
    • 30 Oct 2016 Results assessing efficacy presented at the IDWeek 2016

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