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Open-label, Multicenter, Dose-escalating Phase II Study to Investigate the Safety, Tolerability, and Early Signs of Efficacy of Subcutaneous Administrations of Tadekinig Alfa (IL-18BP) in Patients With Adult -Onset Still's Disease (AoSD) During 12 Weeks

Trial Profile

Open-label, Multicenter, Dose-escalating Phase II Study to Investigate the Safety, Tolerability, and Early Signs of Efficacy of Subcutaneous Administrations of Tadekinig Alfa (IL-18BP) in Patients With Adult -Onset Still's Disease (AoSD) During 12 Weeks

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Tadekinig alfa (Primary)
  • Indications Adult-onset Still's disease
  • Focus Adverse reactions
  • Sponsors AB2 Bio
  • Most Recent Events

    • 22 Feb 2018 Results assessing safety and efficacy published in the Annals of the Rheumatic Diseases.
    • 17 Jun 2017 Results presented at the 18th Annual Congress of the European League Against Rheumatism.
    • 29 Aug 2016 Number of treatment arms changed from 3 to 2.

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