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Phase I trial of EPZ 6438 in children with INI1-deficient solid tumours, including malignant rhabdoid tumours.

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Trial Profile

Phase I trial of EPZ 6438 in children with INI1-deficient solid tumours, including malignant rhabdoid tumours.

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 10 Aug 2017

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At a glance

  • Drugs Tazemetostat (Primary)
  • Indications Rhabdoid tumour; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Epizyme

    • Most Recent Events

    • 04 Aug 2017 According to an Epizyme media release, the company initiated the dose-expansion portion of the study in Jul 2017.
    • 09 Nov 2015 Interim results presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2015
    • 26 Sep 2015 Planned number of patients changed from 40 to 51, as per Epizyme media release.
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