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PIPA: A Phase Ib Study to Assess the Safety, Tolerability and Efficacy of the PI3K Inhibitors, Taselisib (GDC-0032) or Pictilisib (GDC-0941), in Combination With PAlbociclib, With the Subsequent Addition of Fulvestrant in PIK3CA-mutant Breast Cancers

Trial Profile

PIPA: A Phase Ib Study to Assess the Safety, Tolerability and Efficacy of the PI3K Inhibitors, Taselisib (GDC-0032) or Pictilisib (GDC-0941), in Combination With PAlbociclib, With the Subsequent Addition of Fulvestrant in PIK3CA-mutant Breast Cancers

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 02 Nov 2021

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At a glance

  • Drugs Palbociclib (Primary) ; Pictrelisib (Primary) ; Taselisib (Primary) ; Fulvestrant
  • Indications Advanced breast cancer; Colorectal cancer; Endometrial cancer; Head and neck cancer; Lung cancer; Oligodendroglioma; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms PIPA
  • Most Recent Events

    • 15 Nov 2019 Planned End Date changed from 1 Aug 2017 to 1 Jan 2020.
    • 15 Nov 2019 Status changed from recruiting to active, no longer recruiting.
    • 04 Jun 2019 Results (n=20) presented at the 55th Annual Meeting of the American Society of Clinical Oncology.
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