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BI 655066 / ABBV-066 (Risankizumab) Versus Placebo In a Multicenter Randomized Double-blind Study in Patients With Moderate to Severe Chronic Plaque Psoriasis Evaluating the Efficacy and Safety With Randomized Withdrawal and Re-treatment (IMMhance)

Trial Profile

BI 655066 / ABBV-066 (Risankizumab) Versus Placebo In a Multicenter Randomized Double-blind Study in Patients With Moderate to Severe Chronic Plaque Psoriasis Evaluating the Efficacy and Safety With Randomized Withdrawal and Re-treatment (IMMhance)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 11 May 2023

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At a glance

  • Drugs Risankizumab (Primary)
  • Indications Plaque psoriasis
  • Focus Registrational; Therapeutic Use
  • Acronyms IMMhance
  • Sponsors AbbVie; Boehringer Ingelheim; Boehringer Ingelheim Pharma KG

Most Recent Events

  • 21 Mar 2023 Results of pooled analysis (n=1306 from four studies UltIMMa-1 and -2, IMMvent, and IMMhance) assessing racial and ethnic diversity for efficacy and safety outcomes presented at the American Academy of Dermatology annual Meeting 2023
  • 25 Apr 2021 Results of an analysis assessing the efficacy and safety of Risankizumab re-treatment after withdrawal compared with continuous long-term Risankizumab treatment using data from the IMMhance and LIMMitless studies presented at the American Academy of Dermatology Virtual Meeting Experience 2021
  • 25 Apr 2021 Results (n=2101) of post-hoc and pooled analysis of four phase III clinical trials (UltIMMa-1, UltIMMa-2, IMMvent, and IMMhance), presented at the American Academy of Dermatology Virtual Meeting Experience 2021.

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