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A Phase 1 Study Evaluating the Safety and Pharmacokinetics of ABBV-075 in Subjects With Advanced Cancer

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Trial Profile

A Phase 1 Study Evaluating the Safety and Pharmacokinetics of ABBV-075 in Subjects With Advanced Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 May 2021

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At a glance

  • Drugs Mivebresib (Primary) ; Venetoclax (Primary)
  • Indications Acute myeloid leukaemia; Breast cancer; Colorectal cancer; Head and neck cancer; Multiple myeloma; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Pancreatic cancer; Prostate cancer; Small cell lung cancer; Solid tumours; Uveal melanoma
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Sponsors AbbVie
  • Most Recent Events

    • 02 May 2021 Results (n=44; data cutoff: 3 Dec 2019) from AML patients enrolled in dose-escalation cohort published in the Cancer
    • 10 Dec 2019 Results (as of Jan 2019; n=44) presented at the 61st Annual Meeting and Exposition of the American Society of Hematology
    • 16 Aug 2019 Results (n=72) of dose escalation cohort published in the Clinical Cancer Research

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