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A Phase 2 Study of TH-4000 (Tarloxotinib) in Patients With EGFR-Mutant, T790M-Negative, Advanced Non-Small Cell Lung Cancer Progressing on an EGFR Tyrosine Kinase Inhibitor

Trial Profile

A Phase 2 Study of TH-4000 (Tarloxotinib) in Patients With EGFR-Mutant, T790M-Negative, Advanced Non-Small Cell Lung Cancer Progressing on an EGFR Tyrosine Kinase Inhibitor

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 16 Jan 2023

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At a glance

  • Drugs Tarloxotinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Proof of concept; Therapeutic Use
  • Acronyms TH-4000
  • Sponsors Rain Oncology
  • Most Recent Events

    • 29 Dec 2022 According to Rain Oncology media release, Rain Therapeutics has changed its name to Rain Oncology.
    • 29 Sep 2016 Status changed from recruiting to discontinued, considering the the totality of the clinical data obtained in the interim analysis which do not justify further evaluation, according to a Threshold Pharmaceuticals media release.
    • 29 Sep 2016 Interim Results published in a Threshold Pharmaceuticals media release.

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