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Phase I-II Study of Crenolanib Combined With Standard Salvage Chemotherapy, and Crenolanib Combined With 5-Azacitidine in Acute Myeloid Leukemia Patients With FLT3 Activating Mutations

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Trial Profile

Phase I-II Study of Crenolanib Combined With Standard Salvage Chemotherapy, and Crenolanib Combined With 5-Azacitidine in Acute Myeloid Leukemia Patients With FLT3 Activating Mutations

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 16 Jul 2024

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At a glance

  • Drugs Crenolanib (Primary) ; Azacitidine; Cytarabine; Etoposide; Fludarabine; Granulocyte colony-stimulating factors; Idarubicin; Mitoxantrone
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes
  • Focus Therapeutic Use
  • Sponsors AROG Pharmaceuticals

    • Most Recent Events

    • 17 Jul 2020 Status changed from active, no longer recruiting to completed.
    • 04 Dec 2018 Results presented at the 60th Annual Meeting and Exposition of the American Society of Hematology
    • 16 Jul 2018 Planned End Date changed from 1 Apr 2018 to 1 Apr 2020.

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