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A Phase 1, Open-label, Drug Interaction Study to Evaluate the Effect of Guselkumab (CNTO 1959) on Cytochrome P450 Enzyme Activities Following a Single Subcutaneous Administration in Subjects With Moderate to Severe Plaque-type Psoriasis

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Trial Profile

A Phase 1, Open-label, Drug Interaction Study to Evaluate the Effect of Guselkumab (CNTO 1959) on Cytochrome P450 Enzyme Activities Following a Single Subcutaneous Administration in Subjects With Moderate to Severe Plaque-type Psoriasis

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Guselkumab (Primary) ; Caffeine; Dextromethorphan; Midazolam; Omeprazole; Warfarin
  • Indications Plaque psoriasis
  • Focus Pharmacokinetics
  • Sponsors Janssen Research & Development

Most Recent Events

  • 23 Dec 2016 Status changed from active, no longer recruiting to completed.
  • 27 Jun 2016 Status changed from recruiting to active, no longer recruiting.
  • 06 Jun 2016 Planned End Date changed from 1 Oct 2016 to 1 Sep 2016.

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