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A Phase 1a/1b Multicenter, Single-Arm, Open-Label, Dose-Escalation Study to Determine the Maximum Tolerated Dose, Safety, and Preliminary Activity of Oral ACY-241 Alone and in Combination With Pomalidomide and Low-Dose Dexamethasone in Patients With Relapsed or Relapsed-and-Refractory Multiple Myeloma

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A Phase 1a/1b Multicenter, Single-Arm, Open-Label, Dose-Escalation Study to Determine the Maximum Tolerated Dose, Safety, and Preliminary Activity of Oral ACY-241 Alone and in Combination With Pomalidomide and Low-Dose Dexamethasone in Patients With Relapsed or Relapsed-and-Refractory Multiple Myeloma

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 18 Jul 2024

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At a glance

  • Drugs Citarinostat (Primary) ; Dexamethasone (Primary) ; Pomalidomide (Primary)
  • Indications Multiple myeloma
  • Focus Adverse reactions; First in man
  • Sponsors Acetylon Pharmaceuticals; Celgene Corporation

    • Most Recent Events

    • 09 Jul 2024 Status changed from active, no longer recruiting to discontinued.
    • 10 Oct 2023 Planned End Date changed from 2 Jul 2023 to 31 Jan 2024.
    • 10 Oct 2023 Planned primary completion date changed from 30 Jun 2023 to 31 Jan 2024.

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