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Phase II Trial of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

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Trial Profile

Phase II Trial of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 04 Apr 2025

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At a glance

  • Drugs Selumetinib (Primary)
  • Indications Neurofibromatosis 1; Plexiform neurofibroma
  • Focus Therapeutic Use

Most Recent Events

  • 30 Jan 2025 Planned End Date changed from 1 Jan 2025 to 1 Jan 2030.
  • 30 Jan 2025 Planned End Date changed from 1 Jan 2025 to 1 Jan 2030.
  • 30 Jan 2025 Planned primary completion date changed from 1 Jan 2025 to 1 Jan 2028.

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