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A Non-randomized, Phase II Study of Eltrombopag in Combination With Rabbit Anti-thymocyte Globulin/Cyclosporine A (ATG/CsA) in Subjects With Moderate or More Severe Aplastic Anemia Who Have Not Received Prior ATG/Anti-lymphocyte Globulin (ALG)-Based Immunosuppressive Therapy

Trial Profile

A Non-randomized, Phase II Study of Eltrombopag in Combination With Rabbit Anti-thymocyte Globulin/Cyclosporine A (ATG/CsA) in Subjects With Moderate or More Severe Aplastic Anemia Who Have Not Received Prior ATG/Anti-lymphocyte Globulin (ALG)-Based Immunosuppressive Therapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Nov 2022

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At a glance

  • Drugs Eltrombopag (Primary) ; Antithymocyte globulin; Ciclosporin
  • Indications Aplastic anaemia
  • Focus Therapeutic Use
  • Sponsors GlaxoSmithKline; GSK; Novartis; Novartis Pharmaceuticals

Most Recent Events

  • 03 Nov 2022 Results(n=31: from two phase 2 studies (E1201 and E1202 NCT02148133, NCT02404025) assessing the effect of eltrombopag on cytomorphologic findings in Patients With Aplastic Anemia published in the American Journal of Clinical Pathology
  • 05 Oct 2017 Status changed from active, no longer recruiting to completed.
  • 22 May 2017 Planned primary completion date changed from 1 Feb 2017 to 31 Oct 2017.

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