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Long Term Clear Skin Maintenance Treatment Optimization in Patients With Moderate to Severe Chronic Plaque Psoriasis: A Randomized, Multicenter, Open-label With Blinded-assessment, Comparative, 52 Week Study to Evaluate the Efficacy, Safety and Tolerability of Secukinumab 300 mg s.c.

Trial Profile

Long Term Clear Skin Maintenance Treatment Optimization in Patients With Moderate to Severe Chronic Plaque Psoriasis: A Randomized, Multicenter, Open-label With Blinded-assessment, Comparative, 52 Week Study to Evaluate the Efficacy, Safety and Tolerability of Secukinumab 300 mg s.c.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Secukinumab (Primary)
  • Indications Plaque psoriasis
  • Focus Therapeutic Use
  • Acronyms OPTIMISE
  • Sponsors Novartis; Novartis Pharma A.G.
  • Most Recent Events

    • 17 May 2019 Norway, Romania and Serbia were planned locations as per European Clinical Trials Database record.
    • 17 May 2019 Primary endpoint (Non-inferiority of q6w vs q4w dosing) has not been met as per results published in the British Journal of Dermatology.
    • 17 May 2019 Results published in the British Journal of Dermatology

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