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A Phase I, Open-Label, Dose-Escalation Study to Investigate the Safety of ISTH0036, a 'Next Generation' TGF-β2-Selective Antisense Oligonucleotide, in Subjects With Primary Open-Angle Glaucoma Undergoing Trabeculectomy

Trial Profile

A Phase I, Open-Label, Dose-Escalation Study to Investigate the Safety of ISTH0036, a 'Next Generation' TGF-β2-Selective Antisense Oligonucleotide, in Subjects With Primary Open-Angle Glaucoma Undergoing Trabeculectomy

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs ISTH 0036 (Primary)
  • Indications Open-angle glaucoma
  • Focus Adverse reactions; First in man
  • Sponsors Isarna Therapeutics

Most Recent Events

  • 28 Feb 2018 Status changed from active, no longer recruiting to completed.
  • 15 May 2017 Results from this trial published in an Isarna Therapeutics Media Release.
  • 15 May 2017 According to an Isarna Therapeutics media release, data from this trial were presented at The Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO).

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