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An Open Label Non Randomized Access Study of Trametinib for Patients With Advanced Unresectable (Stage IIIc) or Distant Metastatic (Stage IV) BRAF V600E/K Mutation Positive Cutaneous Melanoma

Trial Profile

An Open Label Non Randomized Access Study of Trametinib for Patients With Advanced Unresectable (Stage IIIc) or Distant Metastatic (Stage IV) BRAF V600E/K Mutation Positive Cutaneous Melanoma

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 04 Oct 2022

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At a glance

  • Drugs Trametinib (Primary) ; Dabrafenib
  • Indications Malignant melanoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors GlaxoSmithKline; GSK

Most Recent Events

  • 25 Sep 2022 Results of subgroup analysis assessing efficacy in patients with BRAFV600-mutant melanoma and BM treated with BRAF and MEK inhibitors dabrafenib and trametinib, published in the European Journal of Cancer
  • 06 Jul 2021 Results of an analysis assessing the safety, response to treatment, progression-free survival and factors associated with progression, and stratified the population into risk groups published in the European Journal of Cancer
  • 14 May 2017 Status changed from recruiting to completed.

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