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A Phase I, Multi-center, Open Label, Drug-drug Interaction Study to Assess the Effect of Ceritinib on the Pharmacokinetics of Warfarin and Midazolam Administered as a Two-drug Cocktail in Patients With ALK-positive Advanced Tumors Including Non-small Cell Lung Cancer (NSCLC)

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A Phase I, Multi-center, Open Label, Drug-drug Interaction Study to Assess the Effect of Ceritinib on the Pharmacokinetics of Warfarin and Midazolam Administered as a Two-drug Cocktail in Patients With ALK-positive Advanced Tumors Including Non-small Cell Lung Cancer (NSCLC)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Ceritinib (Primary) ; Midazolam; Warfarin
  • Indications Non-small cell lung cancer
  • Focus Pharmacokinetics
  • Sponsors Novartis; Novartis Pharmaceuticals

    • Most Recent Events

    • 16 Apr 2018 Status changed from active, no longer recruiting to completed.
    • 09 Nov 2017 Planned End Date changed from 22 Sep 2017 to 23 Nov 2017.
    • 09 Nov 2017 Planned primary completion date changed from 22 Sep 2017 to 23 Nov 2017.

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