A Phase II Study of the Combination of Ruxolitinib or Dasatinib With Chemotherapy in Patients With Philadelphia Chromosome (Ph)-Like Acute Lymphoblastic Leukemia (ALL)

Trial Profile

A Phase II Study of the Combination of Ruxolitinib or Dasatinib With Chemotherapy in Patients With Philadelphia Chromosome (Ph)-Like Acute Lymphoblastic Leukemia (ALL)

Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 Dec 2017

At a glance

  • Drugs Dasatinib (Primary) ; Ruxolitinib (Primary) ; Cyclophosphamide; Cytarabine; Dexamethasone; Dexamethasone; Doxorubicin; Filgrastim; Folinic acid; Mercaptopurine; Mesna; Methotrexate; Methylprednisolone; Pegfilgrastim; Prednisone; Rituximab; Vincristine
  • Indications Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 20 Dec 2017 According to NCT this is a phase II study and according to results presented at the 59th ASH this is phase I/II study. I have retained info as per ASH.
    • 12 Dec 2017 Interim results of phase I part of this study (n=9) presented at the 59th Annual Meeting and Exposition of the American Society of Hematology
    • 10 Jun 2017 Biomarkers information updated
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