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A Two Part Protocol Using Double Blind Placebo Control to Assess the Safety, Tolerability, and Pharmacokinetics of Single Escalating Intra-articular Doses Followed by Assessment of Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Intra-articular Dose of the TrkA Inhibitor, GZ389988A, in Patients with Painful Osteoarthritis of the Knee

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Trial Profile

A Two Part Protocol Using Double Blind Placebo Control to Assess the Safety, Tolerability, and Pharmacokinetics of Single Escalating Intra-articular Doses Followed by Assessment of Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Intra-articular Dose of the TrkA Inhibitor, GZ389988A, in Patients with Painful Osteoarthritis of the Knee

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs GZ 389988 (Primary)
  • Indications Osteoarthritis
  • Focus Adverse reactions; First in man; Proof of concept; Therapeutic Use
  • Sponsors Sanofi; Sanofi Genzyme

    • Most Recent Events

    • 26 Oct 2017 Status changed from active, no longer recruiting to completed.
    • 28 Aug 2017 Planned End Date changed from 1 Sep 2017 to 29 Sep 2017.
    • 28 Aug 2017 Planned End Date changed from 1 Sep 2017 to 29 Sep 2017.

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