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First-in-Human Safety, Tolerability, and Functional Activity of ABT-122, a Dual TNF- and IL-17A–Targeted DVD-Ig™, Following Single-Dose Administration in Healthy Subjects

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Trial Profile

First-in-Human Safety, Tolerability, and Functional Activity of ABT-122, a Dual TNF- and IL-17A–Targeted DVD-Ig™, Following Single-Dose Administration in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 31 Jul 2017

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At a glance

  • Drugs Remtolumab (Primary) ; Remtolumab (Primary)
  • Indications Rheumatoid arthritis
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Sponsors AbbVie

    • Most Recent Events

    • 25 Jul 2017 Results of pooled analysis from three phase I studies including this study published in the Clinical Pharmacokinetics
    • 13 Jun 2015 Results presented at the 16th Annual Congress of the European League Against Rheumatism.
    • 13 Jun 2015 Results presented (pooled analysis of 3 phase I trials) at the 16th Annual Congress of the European League Against Rheumatism.

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