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A Phase 1/2a Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of FORE8394 in Patients With Advanced Unresectable Solid Tumors

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Trial Profile

A Phase 1/2a Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of FORE8394 in Patients With Advanced Unresectable Solid Tumors

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 02 May 2025

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At a glance

  • Drugs Plixorafenib (Primary) ; Cobicistat
  • Indications Colorectal cancer; Glioma; Malignant melanoma; Neuroendocrine tumours; Ovarian cancer; Solid tumours; Thyroid cancer
  • Focus Adverse reactions; Pharmacokinetics; Registrational; Therapeutic Use
  • Sponsors Novellus Biopharma; Plexxikon

Most Recent Events

  • 25 Apr 2025 Results presented in the Fore Biotherapeutics Media Release
  • 25 Mar 2025 According to Fore Biotherapeutics media release, company announced that abstract regarding this trial has been selected for poster presentation at the American Association for Cancer Research (AACR) Annual Meeting 2025, taking place April 25-30 in Chicago.
  • 31 Jul 2024 Status changed from active, no longer recruiting to completed.

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